DNA-binding function of c-Myb R2R3 around thermal denaturation temperature
The minimum DNA-binding domain of the transcriptional factor c-Myb R2R3 remarkably fluctuates in the solution. In the present study, we evaluated the protein fluctuation of R2R3 C130I mutant, R2R3*, on its DNA-binding and folding thermodynamics. DNA-binding analysis using isothermal titration calor...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
The Biophysical Society of Japan
2021-04-01
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| Series: | Biophysics and Physicobiology |
| Subjects: | |
| Online Access: | https://doi.org/10.2142/biophysico.bppb-v18.009 |