Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS.

There are numerous studies describing the signaling mechanisms that mediate oligodendrocyte precursor cell (OPC) proliferation and differentiation, although the contribution of the cellular prion protein (PrP(c)) to this process remains unclear. PrP(c) is a glycosyl-phosphatidylinositol (GPI)-anchor...

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Bibliographic Details
Main Authors: Ana Bribián, Xavier Fontana, Franc Llorens, Rosalina Gavín, Manuel Reina, José Manuel García-Verdugo, Juan María Torres, Fernando de Castro, José Antonio del Río
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22529900/?tool=EBI