Integrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression)

Integrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression)

To characterize molecular changes accompanying the stepwise progression to breast cancer and to identify functional target pathways, we performed miRNA and RNA sequencing using MCF10A cell lines based model system that replicates the multi-step progression involving normal, preneoplastic, ductal car...

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Bibliographic Details
Main Authors: Zhenlin Ju, Anjana Bhardwaj, Matthew D. Embury, Harpreet Singh, Preethi H. Gunaratne, Isabelle Bedrosian, Jing Wang
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
basal-like breast cancer
preneoplastic
mirnaomics
rna sequencing
integromics
Online Access:https://www.mdpi.com/2072-6694/12/3/722

Internet

https://www.mdpi.com/2072-6694/12/3/722

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