Combination of olfactory ensheathing cells and human umbilical cord mesenchymal stem cell-derived exosomes promotes sciatic nerve regeneration

Combination of olfactory ensheathing cells and human umbilical cord mesenchymal stem cell-derived exosomes promotes sciatic nerve regeneration

Olfactory ensheathing cells (OECs) are promising seed cells for nerve regeneration. However, their application is limited by the hypoxic environment usually present at the site of injury. Exosomes derived from human umbilical cord mesenchymal stem cells have the potential to regulate the pathologica...

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Bibliographic Details
Main Authors: Yang Zhang, Wen-Tao Wang, Chun-Rong Gong, Chao Li, Mei Shi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
brain-derived neurotrophic factor; cell migration; cell viability; functional recovery; hypoxia; nerve regeneration; sciatic functional index; sciatic nerve injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=10;spage=1903;epage=1911;aulast=

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=10;spage=1903;epage=1911;aulast=

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