Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia

Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia

We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa (l-DOPA)-induced dyskinesia and Parkinson disease (PD). 6-Hydroxydopamine (6-OHDA)-lesioned rats were treated with l-DOPA or physiological saline for 22 days and repeatedly tested for anti...

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Bibliographic Details
Main Authors: Christine Konradi, Jenny E. Westin, Manolo Carta, Molly E. Eaton, Katarzyna Kuter, Andrzej Dekundy, Martin Lundblad, M. Angela Cenci
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Neurobiology of Disease
Subjects:
l-DOPA
Dyskinesia
Parkinson's disease
6-Hydroxydopamine
Gene microarrays
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104001597

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http://www.sciencedirect.com/science/article/pii/S0969996104001597

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