Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD).

Rheumatoid arthritis and periodontitis are two prevalent chronic inflammatory diseases in humans and are associated with each other both clinically and epidemiologically. Recent findings suggest a causative link between periodontal infection and rheumatoid arthritis via bacteria-dependent induction...

Full description

Bibliographic Details
Main Authors: Katarzyna J Maresz, Annelie Hellvard, Aneta Sroka, Karina Adamowicz, Ewa Bielecka, Joanna Koziel, Katarzyna Gawron, Danuta Mizgalska, Katarzyna A Marcinska, Malgorzata Benedyk, Krzysztof Pyrc, Anne-Marie Quirke, Roland Jonsson, Saba Alzabin, Patrick J Venables, Ky-Anh Nguyen, Piotr Mydel, Jan Potempa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3771902?pdf=render