Adaptive amplification and point mutation are independent mechanisms: evidence for various stress-inducible mutation mechanisms.

"Adaptive mutation" denotes a collection of processes in which cells respond to growth-limiting environments by producing compensatory mutants that grow well, apparently violating fundamental principles of evolution. In a well-studied model, starvation of stationary-phase lac(-)Escherichia...

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Bibliographic Details
Main Authors: P J Hastings, Andrew Slack, Joseph F Petrosino, Susan M Rosenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC529313?pdf=render