Functional connection between Rad51 and PML in homology-directed repair.

The promyelocytic leukemia protein (PML) is a tumor suppressor critical for formation of nuclear bodies (NBs) performing important functions in transcription, apoptosis, DNA repair and antiviral responses. Earlier studies demonstrated that simian virus 40 (SV40) initiates replication near PML NBs. H...

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Bibliographic Details
Main Authors: Sergei Boichuk, Liang Hu, Kathleen Makielski, Pier Paolo Pandolfi, Ole V Gjoerup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3187806?pdf=render