Effects of megaplasmid loss on growth of neurotoxigenic Clostridium butyricum strains and botulinum neurotoxin type E expression

Effects of megaplasmid loss on growth of neurotoxigenic Clostridium butyricum strains and botulinum neurotoxin type E expression

Clostridium butyricum strains that atypically produce the botulinum neurotoxin type E (BoNT/E) possess a megaplasmid of unknown functions in their genome. In this study, we cured two botulinum neurotoxigenic C. butyricum type E strains of their megaplasmids, and compared the obtained megaplasmid-cur...

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Bibliographic Details
Main Authors: Concetta eScalfaro, Angelo eIacobino, Laura eGrande, Stefano eMorabito, Giovanna eFranciosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Microbiology
Subjects:
PFGE
microbial growth
Plasmid curing
Megaplasmid
neurotoxigenic Clostridium butyricum type E
botulinum neurotoxin expression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00217/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00217/full

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