Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Upon demyelination, oligodendrocyte progenitor cells (OPCs) are activated and they proliferate, migrate and differentiate into myelin-producing oligodendrocytes. Besides OPCs, neural stem cells (NSC...

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Bibliographic Details
Main Authors: Maria Elena Silva, Simona Lange, Bryan Hinrichsen, Amber R. Philp, Carolina R. Reyes, Diego Halabi, Josselyne B. Mansilla, Peter Rotheneichner, Alerie Guzman de la Fuente, Sebastien Couillard-Despres, Luis F. Bátiz, Robin J. M. Franklin, Ludwig Aigner, Francisco J. Rivera
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
pericytes
neural stem cells
oligodendrogenesis
Lama2
remyelination
vascular niche
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00085/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00085/full

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