Hypoxia destroys the microstructure of microtubules and causes dysfunction of endothelial cells via the PI3K/Stathmin1 pathway

Abstract Background Endothelial cells (EC) are sensitive to changes in the microenvironment, including hypoxia and ischemia. Disruption of the microtubular network has been reported in cases of ischemia. However, the signaling pathways involved in hypoxia-induced microtubular disruption are unknown....

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Bibliographic Details
Main Authors: Huaming Cao, Dongsheng Yu, Xueyun Yan, Bing Wang, Zhiming Yu, Yu Song, Liang Sheng
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Cell & Bioscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13578-019-0283-1