SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

Abstract Background Obesity confers an increased risk and accelerates the progression of multiple tumor types in rodents and humans, including both breast and colon cancer. Because sustained weight loss is rarely achieved, therapeutic approaches to slow or prevent obesity-associated cancer developme...

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Bibliographic Details
Main Authors: Ali R. Nasiri, Marcos R. Rodrigues, Zongyu Li, Brooks P. Leitner, Rachel J. Perry
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cancer & Metabolism
Subjects:
Online Access:https://doi.org/10.1186/s40170-019-0203-1