Cellular Mechanisms of Myocardial Depression in Porcine Septic Shock

Cellular Mechanisms of Myocardial Depression in Porcine Septic Shock

The complex pathogenesis of sepsis and septic shock involves myocardial depression, the pathophysiology of which, however, remains unclear. In this study, cellular mechanisms of myocardial depression were addressed in a clinically relevant, large animal (porcine) model of sepsis and septic shock. Se...

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Bibliographic Details
Main Authors: Dagmar Jarkovska, Michaela Markova, Jan Horak, Lukas Nalos, Jan Benes, Mahmoud Al-Obeidallah, Zdenek Tuma, Jitka Sviglerova, Jitka Kuncova, Martin Matejovic, Milan Stengl
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physiology
Subjects:
sepsis
pig
myocardial depression
calcium
mitochondria
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00726/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00726/full

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