The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples.

Epithelial ovarian cancer (EOC) is the most prevalent form of ovarian cancer and has the highest mortality rate. Novel insight into EOC is required to minimize the morbidity and mortality rates caused by recurrent, drug resistant disease. Although numerous studies have evaluated genome instability i...

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Bibliographic Details
Main Authors: Signe Penner-Goeke, Zelda Lichtensztejn, Megan Neufeld, Jennifer L Ali, Alon D Altman, Mark W Nachtigal, Kirk J McManus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5395197?pdf=render