Common and rare variant analysis in early-onset bipolar disorder vulnerability.

Bipolar disorder is one of the most common and devastating psychiatric disorders whose mechanisms remain largely unknown. Despite a strong genetic contribution demonstrated by twin and adoption studies, a polygenic background influences this multifactorial and heterogeneous psychiatric disorder. To...

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Main Authors: Stéphane Jamain, Sven Cichon, Bruno Etain, Thomas W Mühleisen, Alexander Georgi, Nora Zidane, Lucie Chevallier, Jasmine Deshommes, Aude Nicolas, Annabelle Henrion, Franziska Degenhardt, Manuel Mattheisen, Lutz Priebe, Flavie Mathieu, Jean-Pierre Kahn, Chantal Henry, Anne Boland, Diana Zelenika, Ivo Gut, Simon Heath, Mark Lathrop, Wolfgang Maier, Margot Albus, Marcella Rietschel, Thomas G Schulze, Francis J McMahon, John R Kelsoe, Marian Hamshere, Nicholas Craddock, Markus M Nöthen, Frank Bellivier, Marion Leboyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4128749?pdf=render