Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis

Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis

The insulin receptor substrate (IRS) proteins are a family of cytoplasmic proteins that integrate and coordinate the transmission of signals from the extracellular to the intracellular environment via transmembrane receptors, thus regulating cell growth, metabolism, survival and proliferation. The P...

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Bibliographic Details
Main Authors: João Agostinho Machado-Neto, Bruna Alves Fenerich, Ana Paula Nunes Rodrigues Alves, Jaqueline Cristina Fernandes, Renata Scopim-Ribeiro, Juan Luiz Coelho-Silva, Fabiola Traina
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2018-10-01
Series:Clinics
Subjects:
Insulin Receptor Substrate
Adaptor Protein
Signal Transduction
Hematopoiesis
Leukemia
Myeloproliferative Neoplasms
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000200332&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000200332&lng=en&tlng=en

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