Regulatory role of microRNAs on PTEN signaling

Regulatory role of microRNAs on PTEN signaling

Phosphatase and tensin homolog (PTEN) gene encodes a tumor suppressor protein which is altered in several malignancies. This protein is a negative regulator of the PI3K/AKT signaling. Several transcription factors regulate the expression of PTEN in positive or negative directions. Moreover, numerous...

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Bibliographic Details
Main Authors: Soudeh Ghafouri-Fard, Atefe Abak, Hamed Shoorei, Mahdi Mohaqiq, Jamal Majidpoor, Arezou Sayad, Mohammad Taheri
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
miRNA
PTEN
Cancer
Disorder
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220311781

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http://www.sciencedirect.com/science/article/pii/S0753332220311781

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