The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing

The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing

Summary: The bromodomain protein 4 (BRD4) is an atypical kinase and histone acetyl transferase (HAT) that binds to acetylated histones and contributes to chromatin remodeling and early transcriptional elongation. During transcription, BRD4 travels with the elongation complex. Since most alternative...

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Bibliographic Details
Main Authors: Sheetal Uppal, Anne Gegonne, Qingrong Chen, Petria S. Thompson, Dan Cheng, Jie Mu, Daoud Meerzaman, Hari S. Misra, Dinah S. Singer
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313804

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http://www.sciencedirect.com/science/article/pii/S2211124719313804

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