Myeloid suppressor cell depletion augments antitumor activity in lung cancer.

Myeloid suppressor cell depletion augments antitumor activity in lung cancer.

Myeloid derived suppressor cells (MDSC) are important regulators of immune responses. We evaluated the mechanistic role of MDSC depletion on antigen presenting cell (APC), NK, T cell activities and therapeutic vaccination responses in murine models of lung cancer.Individual antibody mediated depleti...

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Bibliographic Details
Main Authors: Minu K Srivastava, Li Zhu, Marni Harris-White, Upendra K Kar, Min Huang, Ming F Johnson, Jay M Lee, David Elashoff, Robert Strieter, Steven Dubinett, Sherven Sharma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398024?pdf=render

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http://europepmc.org/articles/PMC3398024?pdf=render

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