Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism

Alka(e)nes with chain lengths in C5-C23 range are ideal fuel components. Here, the authors report that high-titer production of alak(e)nes in pathway engineered Yarrowia lipolytica, which is enabled by the finding that acyl-CoA is another substrate of fatty acid photodecarboxylase (FAP).

Bibliographic Details
Main Authors: Jingbo Li, Yongshuo Ma, Nian Liu, Bekir E. Eser, Zheng Guo, Peter Ruhdal Jensen, Gregory Stephanopoulos
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19995-0