Nonparametric goodness‐of‐fit testing for parametric covariate models in pharmacometric analyses

Abstract The characterization of covariate effects on model parameters is a crucial step during pharmacokinetic/pharmacodynamic analyses. Although covariate selection criteria have been studied extensively, the choice of the functional relationship between covariates and parameters, however, has rec...

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Bibliographic Details
Main Authors: Niklas Hartung, Martin Wahl, Abhishake Rastogi, Wilhelm Huisinga
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12614