Evaluation of Dissolution Profiles of a Newly Developed Solid Oral Immediate-Release Formula Containing Alpha-Lipoic Acid

Evaluation of Dissolution Profiles of a Newly Developed Solid Oral Immediate-Release Formula Containing Alpha-Lipoic Acid

Alpha-lipoic acid (ALA, thioctic acid), a naturally-occurring essential dithiol compound, has become a common ingredient in many pharmaceutical and food supplement products (FSP), used in oxidative stress-dependent pathologies; oral bioavailability of ALA is limited by pharmacokinetic particularitie...

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Bibliographic Details
Main Authors: Anca Lucia Pop, Simona Crișan, Maria Bârcă, Anne-Marie Ciobanu, Valentin Nicolae Varlas, Coriolan Pop, Mariana-Ana Pali, Dumitru Cauni, Emma Adriana Ozon, Denisa Udeanu, Simona Trifu, Bogdana Adriana Năsui
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Processes
Subjects:
alpha-lipoic acid
tablets
dissolution rate
formulation effect
dissolution profiles
food supplements
Online Access:https://www.mdpi.com/2227-9717/9/1/176

Internet

https://www.mdpi.com/2227-9717/9/1/176

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