The Archaeal Na+/Ca2+ Exchanger (NCX_Mj) as a Model of Ion Transport for the Superfamily of Ca2+/CA Antiporters

The superfamily of Calcium/Cation (Ca2+/CA) antiporters extrude Ca2+ from the cytosol or subcellular compartments in exchange with Na+, K+, H+, Li+, or Mg2+ and thereby provide a key mechanism for Ca2+ signaling and ion homeostasis in biological systems ranging from bacteria to humans. The structure...

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Bibliographic Details
Main Author: Daniel Khananshvili
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Chemistry
Subjects:
ion
NCX
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.722336/full