Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement

Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement

The aberrant expression of human endogenous retrovirus (HERV) elements of the HERV-W family has been associated with different diseases, including multiple sclerosis (MS). In particular, the expression of the envelope protein (Env) from the multiple sclerosis-associated retrovirus (MSRV), a member o...

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Bibliographic Details
Main Authors: Benjamin Charvet, Josephine M. Reynaud, Geraldine Gourru-Lesimple, Hervé Perron, Patrice N. Marche, Branka Horvat
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
human endogenous retrovirus
multiple sclerosis
MSRV
inflammation
HHV-6A
CD46
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02803/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02803/full

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