Kaempferol Alleviates Oxidative Stress and Apoptosis Through Mitochondria-dependent Pathway During Lung Ischemia-Reperfusion Injury

Kaempferol Alleviates Oxidative Stress and Apoptosis Through Mitochondria-dependent Pathway During Lung Ischemia-Reperfusion Injury

In previous study, we reported that kaempferol ameliorates significantly lung ischemia-reperfusion injury (LIRI), and may be achieved by targeting the SIRT 1 pathway. This study further explored the anti-LIRI mechanism of kaempferol. In vitro, the rat alveolar epithelial cells L2 was cultured and su...

Full description

Bibliographic Details
Main Authors: Chunli Yang, Wenkai Yang, Zhaohui He, Jinghua Guo, Xiaogang Yang, Rongsheng Wang, Hongbo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
kaempferol
lung ischemia-reperfusion injury
mitochondria
apoptosis
oxidative stress
SIRT1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.624402/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.624402/full

Similar Items