Encapsulation of irinotecan in polymeric nanoparticles: Characterization, release kinetic and cytotoxicity evaluation

Objective(s): Irinotecan is a potent anti-cancer drug from camptothecin group which inhibits topoisomerase I. Recently, biodegradable and biocompatible polymers such as poly lactide-co-glycolides (PLGA) have been considered for the preparation of nanoparticles (NPs). Materials and Methods: In this s...

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Bibliographic Details
Main Authors: Heydar Mohammady, Rassoul Dinarvand, Mehdi Esfandyari Manesh, Pedram Ebrahimnejad
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-07-01
Series:Nanomedicine Journal
Subjects:
Online Access:http://nmj.mums.ac.ir/article_7021_7c6da284b1d935c2c2e68f98b745f2ab.pdf