Encapsulation of irinotecan in polymeric nanoparticles: Characterization, release kinetic and cytotoxicity evaluation
Objective(s): Irinotecan is a potent anti-cancer drug from camptothecin group which inhibits topoisomerase I. Recently, biodegradable and biocompatible polymers such as poly lactide-co-glycolides (PLGA) have been considered for the preparation of nanoparticles (NPs). Materials and Methods: In this s...
Main Authors: | Heydar Mohammady, Rassoul Dinarvand, Mehdi Esfandyari Manesh, Pedram Ebrahimnejad |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2016-07-01
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Series: | Nanomedicine Journal |
Subjects: | |
Online Access: | http://nmj.mums.ac.ir/article_7021_7c6da284b1d935c2c2e68f98b745f2ab.pdf |
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