Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence

Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence

Chikungunya virus (CHIKV) and related alphaviruses cause epidemics of acute and chronic musculoskeletal disease. To investigate the mechanisms underlying the failure of immune clearance of CHIKV, we studied mice infected with an attenuated CHIKV strain (181/25) and the pathogenic parental strain (AF...

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Bibliographic Details
Main Authors: David W. Hawman, Julie M. Fox, Alison W. Ashbrook, Nicholas A. May, Kristin M.S. Schroeder, Raul M. Torres, James E. Crowe Jr., Terence S. Dermody, Michael S. Diamond, Thomas E. Morrison
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716308452

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http://www.sciencedirect.com/science/article/pii/S2211124716308452

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