Discovery of human inversion polymorphisms by comparative analysis of human and chimpanzee DNA sequence assemblies.

With a draft genome-sequence assembly for the chimpanzee available, it is now possible to perform genome-wide analyses to identify, at a submicroscopic level, structural rearrangements that have occurred between chimpanzees and humans. The goal of this study was to investigate chromosomal regions th...

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Bibliographic Details
Main Authors: Lars Feuk, Jeffrey R MacDonald, Terence Tang, Andrew R Carson, Martin Li, Girish Rao, Razi Khaja, Stephen W Scherer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1270012?pdf=render