Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Abstract Background Metastatic triple-negative breast cancer (TNBC) is a heterogeneous and incurable disease. Numerous studies have been conducted to seek molecular targets to treat TNBC effectively, but chemotherapy is still the main choice for patients with TNBC. We have previously presented evide...

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Bibliographic Details
Main Authors: Kideok Jin, Niranjan B. Pandey, Aleksander S. Popel
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Breast Cancer Research
Subjects:
Triple negative breast cancer
Tumor microenvironment
Secretome
Drug repurposing
Maraviroc
Tocilizumab
Online Access:http://link.springer.com/article/10.1186/s13058-018-0981-3

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http://link.springer.com/article/10.1186/s13058-018-0981-3

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