GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima

<p>Abstract</p> <p>Background</p> <p>Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sampling based technique for TFBS discovery is attempted through an...

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Bibliographic Details
Main Author: Shida Kazuhito
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/7/486