Hap-E Search 2.0: Improving the Performance of a Probabilistic Donor-Recipient Matching Algorithm Based on Haplotype Frequencies

Hap-E Search 2.0: Improving the Performance of a Probabilistic Donor-Recipient Matching Algorithm Based on Haplotype Frequencies

In the setting of hematopoietic stem cell transplantation, donor-patient HLA matching is the prime donor selection criterion. Matching algorithms provide ordered lists of donors where the probability of a donor to be an HLA match is calculated in cases where either donor or patient HLA typing inform...

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Bibliographic Details
Main Authors: Christine Urban, Alexander H. Schmidt, Jan Andreas Hofmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Medicine
Subjects:
bioinformatics
HSCT
HLA
haplotype frequencies
matching algorithm
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00032/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00032/full

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