Human Spinal Motor Neurons Are Particularly Vulnerable to Cerebrospinal Fluid of Amyotrophic Lateral Sclerosis Patients

Human Spinal Motor Neurons Are Particularly Vulnerable to Cerebrospinal Fluid of Amyotrophic Lateral Sclerosis Patients

Amyotrophic lateral sclerosis (ALS) is the most common and devastating motor neuron (MN) disease. Its pathophysiological cascade is still enigmatic. More than 90% of ALS patients suffer from sporadic ALS, which makes it specifically demanding to generate appropriate model systems. One interesting as...

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Bibliographic Details
Main Authors: Stefan Bräuer, René Günther, Jared Sterneckert, Hannes Glaß, Andreas Hermann
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis
ALS
cerebrospinal fluid
Golgi fragmentation
superoxide dismutase 1
fused in sarcoma
Online Access:https://www.mdpi.com/1422-0067/21/10/3564

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https://www.mdpi.com/1422-0067/21/10/3564

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