Radiological and Histopathological Outcome of Giant Cell Tumor of Femur with Denosumab Treatment: A Case Report

Giant Cell Tumour of Bone (GCTB) is a benign but locally aggressive osteolytic skeletal neoplasm of young adults consisting of giant cells expressing RANK (Receptor Activator of Nuclear Factor-κB) and mesenchymal spindle-like stromal cells expressing RANKL (RANK ligand). The interaction of these c...

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Bibliographic Details
Main Authors: Preethi Dileep Menon, R. Krishnakumar, Annie Jojo
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-12-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/9070/22172_CE[Ra1]_F(RK)_PF1(GU_SRI)_PFA(AK)_PF2(PAG).pdf