Screening significantly hypermethylated genes in fetal tissues compared with maternal blood using a methylated-CpG island recovery assay-based microarray

Screening significantly hypermethylated genes in fetal tissues compared with maternal blood using a methylated-CpG island recovery assay-based microarray

<p>Abstract</p> <p>Background</p> <p>The noninvasive prenatal diagnosis procedures that are currently used to detect genetic diseases do not achieve desirable levels of sensitivity and specificity. Recently, fetal methylated DNA biomarkers in maternal peripheral blood h...

Full description

Bibliographic Details
Main Authors: Yin Aihua, Zhang Xiangzhong, Wu Jing, Du Li, He Tianwen, Zhang Xiaozhuang
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Medical Genomics
Subjects:
CpG islands methylation
Methyl-CpG binding protein
Microarray
Combined bisulfite restriction analysis
Online Access:http://www.biomedcentral.com/1755-8794/5/26

Internet

http://www.biomedcentral.com/1755-8794/5/26

Similar Items