Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy

Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy

In recent years, molecular characterization and management of patients with systemic mastocytosis (SM) have greatly benefited from the application of advanced technologies. Highly sensitive and accurate assays for <i>KIT</i> D816V mutation detection and quantification have allowed the sw...

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Bibliographic Details
Main Authors: Margherita Martelli, Cecilia Monaldi, Sara De Santis, Samantha Bruno, Manuela Mancini, Michele Cavo, Simona Soverini
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
systemic mastocytosis
KIT tyrosine kinase
allele burden
next-generation sequencing
SETD2 histone methyltransferase
Online Access:https://www.mdpi.com/1422-0067/21/11/3987

Internet

https://www.mdpi.com/1422-0067/21/11/3987

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