Biotransformation of Phytosterols to Androst-1,4-Diene-3,17-Dione by <i>Mycobacterium </i>sp. ZFZ Expressing 3-Ketosteroid-Δ<sup>1</sup>-Dehydrogenase

As an important hormone drug intermediate, androst-1,4-diene-3,17-dione can be bio-converted from phytosterols. However, separation and purification in the downstream process are very difficult due to the similarity in structure and physiological characteristics between ADD and androstenedione (AD)....

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Bibliographic Details
Main Authors: Xiangcen Liu, Ruijie Zhang, Zhiwei Bao, Chenyang Yuan, Huijin Cao, Jiping Shi, Junsong Sun, Baoguo Zhang
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/10/6/663