Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming

Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming

Tumor-secreted extracellular vesicles (EVs) have been identified as mediators of cancer–host intercellular communication and shown to support pre-metastatic niche formation by modulating stromal cells at future metastatic sites. While osteosarcoma, the most common primary malignant bone tumor in chi...

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Bibliographic Details
Main Authors: Alekhya Mazumdar, Joaquin Urdinez, Aleksandar Boro, Jessica Migliavacca, Matthias J.E. Arlt, Roman Muff, Bruno Fuchs, Jess Gerrit Snedeker, Ana Gvozdenovic
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
osteosarcoma
extracellular vesicles
lung fibroblasts
tumor microenvironment
tumor-host interactions
Online Access:https://www.mdpi.com/1422-0067/21/15/5451

Internet

https://www.mdpi.com/1422-0067/21/15/5451

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