Epigenetics of Estrogen Receptor Signaling: Role in Hormonal Cancer Progression and Therapy
Estrogen receptor (ERa) signaling plays a key role in hormonal cancer progression. ERa is a ligand-dependent transcription factor that modulates gene transcription via recruitment to the target gene chromatin. Emerging evidence suggests that ERa signaling has the potential to contribute to epigeneti...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-03-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/3/2/1691/ |