Ionizing Radiation Reduces TKI Resistance Caused by T790M Mutation in NSCLC Cell Lines

Background and objective Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), which targets EGFR, plays an important role in non-small cell lung cancer (NSCLC) treatment. Patients with somatic activating mutations in the EGFR gene exhibit significant initial response but eventually...

Full description

Bibliographic Details
Main Authors: Jing LI, Xinhu WU, Zhen WANG, Zetian SHEN, Ni SUN, Xixu ZHU
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2015-08-01
Series:Chinese Journal of Lung Cancer
Subjects:
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2015.08.02