ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis.

Cell polarization via asymmetrical distribution of structures or molecules is essential for diverse cellular functions and development of organisms, but how polarity is developmentally controlled has been poorly understood. In plants, the asymmetrical distribution of the PIN-FORMED (PIN) proteins in...

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Bibliographic Details
Main Authors: Shingo Nagawa, Tongda Xu, Deshu Lin, Pankaj Dhonukshe, Xingxing Zhang, Jiri Friml, Ben Scheres, Ying Fu, Zhenbiao Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3317906?pdf=render