Insights into the evolutionary origins of clostridial neurotoxins from analysis of the <it>Clostridium botulinum </it>strain A neurotoxin gene cluster

<p>Abstract</p> <p>Background</p> <p>Clostridial neurotoxins (CNTs) are the most deadly toxins known and causal agents of botulism and tetanus neuroparalytic diseases. Despite considerable progress in understanding CNT structure and function, the evolutionary origins of...

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Bibliographic Details
Main Authors: Meiering Elizabeth M, Müller Kirsten M, Lynch Michael DJ, Doxey Andrew C, McConkey Brendan J
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/8/316