Detection of Vascular Reactive Oxygen Species in Experimental Atherosclerosis by High-Resolution Near-Infrared Fluorescence Imaging Using VCAM-1-Targeted Liposomes Entrapping a Fluorogenic Redox-Sensitive Probe

Excessive production of reactive oxygen species (ROS) and the ensuing oxidative stress are instrumental in all phases of atherosclerosis. Despite the major achievements in understanding the regulatory pathways and molecular sources of ROS in the vasculature, the specific detection and quantification...

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Bibliographic Details
Main Authors: Simona-Adriana Manea, Mihaela-Loredana Vlad, Daniela Rebleanu, Alexandra-Gela Lazar, Ioana Madalina Fenyo, Manuela Calin, Maya Simionescu, Adrian Manea
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6685612