Lymphocytic choriomeningitis virus infection in FVB mouse produces hemorrhagic disease.

The viral family Arenaviridae includes a number of viruses that can cause hemorrhagic fever in humans. Arenavirus infection often involves multiple organs and can lead to capillary instability, impaired hemostasis, and death. Preclinical testing for development of antiviral or therapeutics is in par...

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Bibliographic Details
Main Authors: Frederick J Schnell, Sarah Sundholm, Stacy Crumley, Patrick L Iversen, Dan V Mourich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3531503?pdf=render