Bioconversion variation of ginsenoside CK mediated by human gut microbiota from healthy volunteers and colorectal cancer patients

Bioconversion variation of ginsenoside CK mediated by human gut microbiota from healthy volunteers and colorectal cancer patients

Abstract Background Ginsenoside CK (GCK) serves as the potential anti-colorectal cancer (CRC) protopanaxadiol (PPD)-type saponin, which could be mainly bio-converted to yield PPD by gut microbiota. Meanwhile, the anti-CRC effects of GCK could be altered by gut microbiota due to their different diver...

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Bibliographic Details
Main Authors: Yin-Ping Guo, Li Shao, Li Wang, Man-Yun Chen, Wei Zhang, Wei-Hua Huang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Chinese Medicine
Subjects:
Ginsenoside CK
Gut microbiota
LC-MS/MS
Colorectal cancer
16S rRNA gene sequencing
Online Access:https://doi.org/10.1186/s13020-021-00436-z

Internet

https://doi.org/10.1186/s13020-021-00436-z

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