Leukemia microvesicles affect healthy hematopoietic stem cells

Microvesicles are released by different cell types and shuttle mRNAs and microRNAs which have the possibility to transfer genetic information to a target cell and alter its function. Acute myeloid leukemia is a malignant disorder, and leukemic cells occupy all the bone marrow microenvironment. In th...

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Bibliographic Details
Main Authors: Farnaz Razmkhah, Masoud Soleimani, Davood Mehrabani, Mohammad Hossein Karimi, Sedigheh Amini Kafi-abad, Mani Ramzi, Mahdiyar Iravani Saadi, Javad Kakoui
Format: Article
Language:English
Published: IOS Press 2017-02-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317692234