A pyrexic effect of FGF21 independent of energy expenditure and UCP1

A pyrexic effect of FGF21 independent of energy expenditure and UCP1

Objective: Administration of FGF21 to mice reduces body weight and increases body temperature. The increase in body temperature is generally interpreted as hyperthermia, i.e. a condition secondary to the increase in energy expenditure (heat production). Here, we examine an alternative hypothesis: th...

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Bibliographic Details
Main Authors: Petr Zouhar, Petra Janovska, Sara Stanic, Kristina Bardova, Jiri Funda, Blanka Haberlova, Birgitte Andersen, Martin Rossmeisl, Barbara Cannon, Jan Kopecky, Jan Nedergaard
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Molecular Metabolism
Subjects:
UCP1
Thermoneutrality
Beiging/browning
Obesity
Body temperature control
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782100171X

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http://www.sciencedirect.com/science/article/pii/S221287782100171X

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