Platycodon grandiflorum Saponins attenuate scrotal heat-induced spermatogenic damage via inhibition of oxidative stress and apoptosis in mice

Platycodon grandiflorum Saponins attenuate scrotal heat-induced spermatogenic damage via inhibition of oxidative stress and apoptosis in mice

The aim of the present study was designed to investigate that Platycodon grandiflorum saponins (PGS) exerted protective effects against testicular injury induced by scrotal hyperthermia. PGS (15, 30 mg/kg) were administered intragastrically to mice for 14 days, then exposed to a single scrotal heat...

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Bibliographic Details
Main Authors: Jing Leng, Jin-gang Hou, Cheng-lin Fu, Shen Ren, Shuang Jiang, Ying-ping Wang, Chen Chen, Zi Wang, Wei Li
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Functional Foods
Subjects:
Platycodon grandiflorum Saponins
Heat stress
Oxidative stress
Apoptosis
MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619300581

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http://www.sciencedirect.com/science/article/pii/S1756464619300581

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