Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks
Epithelial-to-mesenchymal transition (EMT) is a key step in development, wound healing, and cancer development. It involves cooperation of signaling pathways, such as transformation growth factor-β (TGF-β), Sonic Hedgehog (SHH), and WNT pathways. These signaling pathways crosstalk to each other and...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-03-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | http://www.mdpi.com/2077-0383/5/4/41 |