Enhancement of Radiation Effectiveness in Cervical Cancer Cells by Combining Ionizing Radiation with Hyperthermia and Molecular Targeting Agents

Enhancement of Radiation Effectiveness in Cervical Cancer Cells by Combining Ionizing Radiation with Hyperthermia and Molecular Targeting Agents

Hyperthermia (HT) and molecular targeting agents can be used to enhance the effect of radiotherapy (RT). The purpose of this paper is to evaluate radiation sensitization by HT and different molecular targeting agents (Poly [ADP-ribose] polymerase 1 inhibitor, PARP1-i; DNA-dependent protein kinase ca...

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Bibliographic Details
Main Authors: Marloes IJff, Bregje van Oorschot, Arlene L. Oei, Przemek M. Krawczyk, Hans M. Rodermond, Lukas J. A. Stalpers, H. Petra Kok, Johannes Crezee, Nicolaas A. P. Franken
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
radiation sensitization
radio enhancement, linear-quadratic model
hyperthermia
PARP1-i
DNA-PKcs-i
HSP90-i
Online Access:http://www.mdpi.com/1422-0067/19/8/2420

Internet

http://www.mdpi.com/1422-0067/19/8/2420

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